Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs

Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs

Abstract Blastocyst complementation by pluripotent stem cell (PSC) injection is believed to be the most promising method to generate xenogeneic organs. However, ethical issues prevent the study of human chimeras in the late embryonic stage of development. Primate embryonic stem cells (ESCs), which h...

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Bibliographic Details
Main Authors: Rui Fu, Dawei Yu, Jilong Ren, Chongyang Li, Jing Wang, Guihai Feng, Xuepeng Wang, Haifeng Wan, Tianda Li, Libin Wang, Ying Zhang, Tang Hai, Wei Li, Qi Zhou
Format: Article
Language:English
Published: SpringerOpen 2019-11-01
Series:Protein & Cell
Subjects:
embryonic stem cells
blastocyst complementation
cynomolgus monkey
pig
interspecies chimera
organ reconstruction
Online Access:https://doi.org/10.1007/s13238-019-00676-8

Internet

https://doi.org/10.1007/s13238-019-00676-8

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