Mouse lung and spleen natural killer cells have phenotypic and functional differences, in part influenced by macrophages.

NK cells are lymphocytes of the innate immune system which are a first line of defense against infections and tumor cells, in bone marrow and peripheral organs like lung and spleen. The lung is an organ in contact with respiratory pathogens and the site of inflammatory disorders triggered by the res...

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Bibliographic Details
Main Authors: Tatiana Michel, Aurélie Poli, Olivia Domingues, Marion Mauffray, Maud Thérésine, Nicolaas H C Brons, François Hentges, Jacques Zimmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3515449?pdf=render