Gab Docking Proteins in Cardiovascular Disease, Cancer, and Inflammation

The docking proteins of the Grb2-associated binder (Gab) family have emerged as crucial signaling compartments in metazoans. In mammals, the Gab proteins, consisting of Gab1, Gab2, and Gab3, are involved in the amplification and integration of signal transduction evoked by a variety of extracellular...

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Bibliographic Details
Main Authors: Yoshikazu Nakaoka, Issei Komuro
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2013/141068