Acute lung injury and acute kidney injury are established by four hours in experimental sepsis and are improved with pre, but not post, sepsis administration of TNF-α antibodies.

Acute kidney injury (AKI) and acute lung injury (ALI) are serious complications of sepsis. AKI is often viewed as a late complication of sepsis. Notably, the onset of AKI relative to ALI is unclear as routine measures of kidney function (BUN and creatinine) are insensitive and increase late. In this...

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Bibliographic Details
Main Authors: Rhea Bhargava, Christopher J Altmann, Ana Andres-Hernando, Ryan G Webb, Kayo Okamura, Yimu Yang, Sandor Falk, Eric P Schmidt, Sarah Faubel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827109?pdf=render