TRPM2 Non-Selective Cation Channels in Liver Injury Mediated by Reactive Oxygen Species
TRPM2 channels admit Ca<sup>2+</sup> and Na<sup>+</sup> across the plasma membrane and release Ca<sup>2+</sup> and Zn<sup>2+</sup> from lysosomes. Channel activation is initiated by reactive oxygen species (ROS), leading to a subsequent increase in ADP...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/10/8/1243 |