The Drug Excipient Cyclodextrin Interacts With -Luciferin and Interferes With Bioluminescence Imaging
Cyclodextrins are well-characterized, barrel-shaped molecules that can solubilize organic small molecules in aqueous solution via host–guest interactions. As such, cyclodextrins are used as excipients for experimental therapeutics in vivo. We observed unanticipated modifications to bioluminescence i...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi - SAGE Publishing
2016-01-01
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| Series: | Molecular Imaging |
| Online Access: | https://doi.org/10.1177/1536012115625225 |