Nanoparticle vaccines encompassing the respiratory syncytial virus (RSV) G protein CX3C chemokine motif induce robust immunity protecting from challenge and disease.

Nanoparticle vaccines encompassing the respiratory syncytial virus (RSV) G protein CX3C chemokine motif induce robust immunity protecting from challenge and disease.

Nanoparticle vaccines were produced using layer-by-layer fabrication and incorporating respiratory syncytial virus (RSV) G protein polypeptides comprising the CX3C chemokine motif. BALB/c mice immunized with G protein nanoparticle vaccines produced a neutralizing antibody response that inhibited RSV...

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Bibliographic Details
Main Authors: Patricia A Jorquera, Youngjoo Choi, Katie E Oakley, Thomas J Powell, James G Boyd, Naveen Palath, Lia M Haynes, Larry J Anderson, Ralph A Tripp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3769300?pdf=render

Internet

http://europepmc.org/articles/PMC3769300?pdf=render

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