Gut microbiota dysbiosis is associated with inflammation and bacterial translocation in mice with CCl4-induced fibrosis.

BACKGROUND: Gut is the major source of endogenous bacteria causing infections in advanced cirrhosis. Intestinal barrier dysfunction has been described in cirrhosis and account for an increased bacterial translocation rate. HYPOTHESIS AND AIMS: We hypothesize that microbiota composition may be affect...

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Bibliographic Details
Main Authors: Isabel Gómez-Hurtado, Arlette Santacruz, Gloria Peiró, Pedro Zapater, Ana Gutiérrez, Miguel Pérez-Mateo, Yolanda Sanz, Rubén Francés
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3146520?pdf=render