Viral Persistence and Chronicity in Hepatitis C Virus Infection: Role of T-Cell Apoptosis, Senescence and Exhaustion

Viral Persistence and Chronicity in Hepatitis C Virus Infection: Role of T-Cell Apoptosis, Senescence and Exhaustion

Hepatitis C virus (HCV) represents a challenging global health threat to ~200 million infected individuals. Clinical data suggest that only ~10–15% of acutely HCV-infected individuals will achieve spontaneous viral clearance despite exuberant virus-specific immune responses, which is large...

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Bibliographic Details
Main Authors: Muttiah Barathan, Rosmawati Mohamed, Yean K. Yong, Meganathan Kannan, Jamuna Vadivelu, Alireza Saeidi, Marie Larsson, Esaki Muthu Shankar
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Cells
Subjects:
apoptosis
viral persistence
hepatitis C virus
immunity
chronic infection
Online Access:http://www.mdpi.com/2073-4409/7/10/165

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http://www.mdpi.com/2073-4409/7/10/165

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