Therapeutic effects of human mesenchymal stem cells in Wistar-Kyoto rats with anti-glomerular basement membrane glomerulonephritis.

INTRODUCTION: Multipotent mesenchymal stem cells (MSCs) have become a promising therapeutic approach in many clinical conditions. The hypothesis that MSCs can provide a potential therapy for human anti-glomerular basement membrane (GBM) glomerulonephritis (GN) was tested. METHODS: Nephrotoxic serum...

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Main Authors: Taihei Suzuki, Masayuki Iyoda, Takanori Shibata, Hirokazu Ohtaki, Kei Matsumoto, Yuki Shindo-Hirai, Yoshihiro Kuno, Yukihiro Wada, Yasutaka Yamamoto, Mio Kawaguchi, Seiji Shioda, Tadao Akizawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3691173?pdf=render