DNA Methylation, Nuclear Organization, and Cancer

The dramatic re-organization of the cancer cell nucleus creates telltale morphological features critical for pathological staging of tumors. In addition, the changes to the mutational and epigenetic landscape in cancer cells alter the structure and stability of the genome and directly contribute to...

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Bibliographic Details
Main Authors: Bhavani P. Madakashira, Kirsten C. Sadler
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00076/full