Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models of type1 diabetes

Infiltration of immune cells to the pancreatic islets precedes clinical symptoms of type 1 diabetes, and lack of methods to detect this insulitis impedes early interventions. Here the authors report a contrast enhanced ultrasound method that can detect early insulitis in mouse models of type 1 diabe...

Full description

Bibliographic Details
Main Authors: David G. Ramirez, Eric Abenojar, Christopher Hernandez, David S. Lorberbaum, Lucine A. Papazian, Samantha Passman, Vinh Pham, Agata A. Exner, Richard K. P. Benninger
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15957-8