Protocol dependence of sequencing-based gene expression measurements.

RNA Seq provides unparalleled levels of information about the transcriptome including precise expression levels over a wide dynamic range. It is essential to understand how technical variation impacts the quality and interpretability of results, how potential errors could be introduced by the protoc...

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Bibliographic Details
Main Authors: Tal Raz, Philipp Kapranov, Doron Lipson, Stan Letovsky, Patrice M Milos, John F Thompson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3089619?pdf=render