microRNA-130a-5p suppresses myocardial ischemia reperfusion injury by downregulating the HMGB2/NF-κB axis

microRNA-130a-5p suppresses myocardial ischemia reperfusion injury by downregulating the HMGB2/NF-κB axis

Abstract Background Myocardial ischemia reperfusion injury (MIRI) is defined as tissue injury in the pathological process of progressive aggravation in ischemic myocardium after the occurrence of acute coronary artery occlusion. Research has documented the involvement of microRNAs (miRs) in MIRI. Ho...

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Bibliographic Details
Main Authors: Yong Li, Hongbo Zhang, Zhanhu Li, Xiaoju Yan, Yuan Li, Shuai Liu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Cardiovascular Disorders
Subjects:
Myocardium ischemia reperfusion injury
microRNA-130a-5p
HMGB2
NF-κb pathway
Oxidative stress
Mitochondrial disorder
Online Access:https://doi.org/10.1186/s12872-020-01742-4

Internet

https://doi.org/10.1186/s12872-020-01742-4

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