The Significance of Hypothiocyanite Production via the Pendrin/DUOX/Peroxidase Pathway in the Pathogenesis of Asthma

Inhaled corticosteroids (ICSs) are used as first-line drugs for asthma, and various novel antiasthma drugs targeting type 2 immune mediators are now under development. However, molecularly targeted drugs are expensive, creating an economic burden on patients. We and others previously found pendrin/S...

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Bibliographic Details
Main Authors: Kenji Izuhara, Shoichi Suzuki, Masahiro Ogawa, Satoshi Nunomura, Yasuhiro Nanri, Yasutaka Mitamura, Tomohito Yoshihara
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2017/1054801