A Novel Method for Identifying Essential Proteins Based on Non-negative Matrix Tri-Factorization

Identification of essential proteins is very important for understanding the basic requirements to sustain a living organism. In recent years, there has been an increasing interest in using computational methods to predict essential proteins based on protein–protein interaction (PPI) networks or fus...

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Bibliographic Details
Main Authors: Zhihong Zhang, Meiping Jiang, Dongjie Wu, Wang Zhang, Wei Yan, Xilong Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.709660/full