Cytotoxicity of some 1-(2,4-dihydroxyphenyl)-3-(4-phenylpiperidin-1-yl) prop-2-en-1-one derivatives using MTT assay

Cytotoxicity of some 1-(2,4-dihydroxyphenyl)-3-(4-phenylpiperidin-1-yl) prop-2-en-1-one derivatives using MTT assay

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Some N-substituted piperidine structures were synthesized and evaluated for cytotoxicity. The N-substituted piperidine with propene substructure could be considered as a lead structure for further sudies of structure activity relationship to develop more potent compounds in future. The compounds wer...

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Bibliographic Details
Main Authors: Farzaneh Fesahat, Mehdi Khoshneviszadeh, Alireza Foroumadi, Alireza Vahidi, Maryam Fereidounpour, Amirhossein Sakhteman
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2015-03-01
Series:Trends in Pharmaceutical Sciences
Subjects:
Piperidine
Cytotoxicity
Breast cancer
Online Access:http://tips.sums.ac.ir/index.php/TiPS/article/view/13/10

Internet

http://tips.sums.ac.ir/index.php/TiPS/article/view/13/10

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