Epigenetic Regulation of Claudin-1 in the Development of Ovarian Cancer Recurrence and Drug Resistance

Epigenetic Regulation of Claudin-1 in the Development of Ovarian Cancer Recurrence and Drug Resistance

Over 21,000 women are diagnosed with ovarian cancer (OC) in the United States each year and over half that number succumb to this disease annually, often due to recurrent disease. A deeper understanding of the molecular events associated with recurrent disease is needed to identify potential targets...

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Bibliographic Details
Main Authors: Zachary R. Visco, Gregory Sfakianos, Carole Grenier, Marie-Helene Boudreau, Sabrina Simpson, Isabel Rodriguez, Regina Whitaker, Derek Y. Yao, Andrew Berchuck, Susan K. Murphy, Zhiqing Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
ovarian cancer
DNA methylation
epigenetic
chemosensitivity
tumor xenograft
recurrent ovarian cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.620873/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.620873/full

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