AmpliSeq Screening of Genes Encoding the C-Type Lectin Receptors and Their Signaling Components Reveals a Common Variant in MASP1 Associated with Pulmonary Tuberculosis in an Indian Population

AmpliSeq Screening of Genes Encoding the C-Type Lectin Receptors and Their Signaling Components Reveals a Common Variant in MASP1 Associated with Pulmonary Tuberculosis in an Indian Population

Tuberculosis (TB) is a multifactorial disease governed by bacterial, host and environmental factors. On the host side, growing evidence shows the crucial role that genetic variants play in the susceptibility to Mycobacterium tuberculosis (Mtb) infection. Such polymorphisms have been described in gen...

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Bibliographic Details
Main Authors: Tilman E. Klassert, Surabhi Goyal, Magdalena Stock, Dominik Driesch, Abid Hussain, Luis Carlos Berrocal-Almanza, Rajashekar Myakala, Gaddam Sumanlatha, Vijayalakshmi Valluri, Niyaz Ahmed, Ralf R. Schumann, Carlos Flores, Hortense Slevogt
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
C-type lectin receptor
MASP1
pulmonary tuberculosis
complement
AmpliSeq
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00242/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00242/full

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