MSIFinder: a python package for detecting MSI status using random forest classifier

MSIFinder: a python package for detecting MSI status using random forest classifier

Abstract Background Microsatellite instability (MSI) is a common genomic alteration in colorectal cancer, endometrial carcinoma, and other solid tumors. MSI is characterized by a high degree of polymorphism in microsatellite lengths owing to the deficiency in the mismatch repair system. Based on the...

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Bibliographic Details
Main Authors: Tao Zhou, Libin Chen, Jing Guo, Mengmeng Zhang, Yanrui Zhang, Shanbo Cao, Feng Lou, Haijun Wang
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Bioinformatics
Subjects:
Microsatellite instability
Genome sequencing
Machine learning technology
Random forest classifier
Immunotherapy
Online Access:https://doi.org/10.1186/s12859-021-03986-z

Internet

https://doi.org/10.1186/s12859-021-03986-z

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