Small Molecules and Peptides Targeting Glial Cell Line-Derived Neurotrophic Factor Receptors for the Treatment of Neurodegeneration

Small Molecules and Peptides Targeting Glial Cell Line-Derived Neurotrophic Factor Receptors for the Treatment of Neurodegeneration

Glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) are able to promote the survival of multiple neuronal populations in the body and, therefore, hold considerable promise for disease-modifying treatments of diseases and conditions caused by neurodegeneration. Available data rev...

Full description

Bibliographic Details
Main Authors: Yulia A. Sidorova, Mart Saarma
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs), receptor tyrosine kinase Rearranged in Transfection (RET)
RET agonist
GFL mimetic
small molecule
Parkinson’s disease
neuropathic pain
Online Access:https://www.mdpi.com/1422-0067/21/18/6575

Internet

https://www.mdpi.com/1422-0067/21/18/6575

Similar Items