Unified Least Squares Methods for the Evaluation of Diagnostic Tests With the Gold Standard

Unified Least Squares Methods for the Evaluation of Diagnostic Tests With the Gold Standard

The article proposes a unified least squares method to estimate the receiver operating characteristic (ROC) parameters for continuous and ordinal diagnostic tests, such as cancer biomarkers. The method is based on a linear model framework using the empirically estimated sensitivities and specificiti...

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Bibliographic Details
Main Authors: Liansheng Larry Tang, Ao Yuan, John Collins, Xuan Che, Leighton Chan
Format: Article
Language:English
Published: SAGE Publishing 2017-02-01
Series:Cancer Informatics
Online Access:https://doi.org/10.1177/1176935116686063

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