Unified Least Squares Methods for the Evaluation of Diagnostic Tests With the Gold Standard

The article proposes a unified least squares method to estimate the receiver operating characteristic (ROC) parameters for continuous and ordinal diagnostic tests, such as cancer biomarkers. The method is based on a linear model framework using the empirically estimated sensitivities and specificiti...

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Bibliographic Details
Main Authors: Liansheng Larry Tang, Ao Yuan, John Collins, Xuan Che, Leighton Chan
Format: Article
Language:English
Published: SAGE Publishing 2017-02-01
Series:Cancer Informatics
Online Access:https://doi.org/10.1177/1176935116686063