Crosstalk within a functional INO80 complex dimer regulates nucleosome sliding

Several chromatin remodellers have the ability to space nucleosomes on DNA. For ISWI remodellers, this involves an interplay between H4 histone tails, the AutoN and NegC motifs of the motor domains that together regulate ATPase activity and sense the length of DNA flanking the nucleosome. By contras...

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Bibliographic Details
Main Authors: Oliver Willhoft, Elizabeth A McCormack, Ricardo J Aramayo, Rohan Bythell-Douglas, Lorraine Ocloo, Xiaodong Zhang, Dale B Wigley
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/25782