The m6A Methyltransferase METTL14-Mediated N6-Methyladenosine Modification of PTEN mRNA Inhibits Tumor Growth and Metastasis in Stomach Adenocarcinoma

The m6A Methyltransferase METTL14-Mediated N6-Methyladenosine Modification of PTEN mRNA Inhibits Tumor Growth and Metastasis in Stomach Adenocarcinoma

BackgroundStomach adenocarcinoma (STAD) is a common reason for tumor-related fatalities globally, as it results in distant metastasis. Methyltransferase-like 14 (METTL14), a notable RNA N6-adenosine methyltransferase (m6A), plays a significant role in the growth of tumor through controlling the RNA...

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Bibliographic Details
Main Authors: Qi Yao, Lanzhen He, Xucan Gao, Na Tang, Lifen Lin, Xiaofang Yu, Dong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
METTL14
STAD
Pten
m6A modification
tumor growth
metastasis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.699749/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.699749/full

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