PPARG in Human Adipogenesis: Differential Contribution of Canonical Transcripts and Dominant Negative Isoforms

The nuclear receptor PPARγ is a key regulator of adipogenesis, and alterations of its function are associated with different pathological processes related to metabolic syndrome. We recently identified two PPARG transcripts encoding dominant negative PPARγ isoforms. The existence of different PPARG...

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Bibliographic Details
Main Authors: M. Aprile, M. R. Ambrosio, V. D'Esposito, F. Beguinot, P. Formisano, V. Costa, A. Ciccodicola
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2014/537865