Biophysical Characterization of CD6—TCR/CD3 Interplay in T Cells

Biophysical Characterization of CD6—TCR/CD3 Interplay in T Cells

Activation of the T cell receptor (TCR) on the T cell through ligation with antigen-MHC complex of an antigen-presenting cell (APC) is an essential process in the activation of T cells and induction of the subsequent adaptive immune response. Upon activation, the TCR, together with its associated co...

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Bibliographic Details
Main Authors: Marjolein B. M. Meddens, Svenja F. B. Mennens, F. Burcu Celikkol, Joost te Riet, Johannes S. Kanger, Ben Joosten, J. Joris Witsenburg, Roland Brock, Carl G. Figdor, Alessandra Cambi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
T cell
immunological synapse
T-cell receptor (TCR)
CD3
CD6
membrane receptor
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02333/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02333/full

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