Arsenic trioxide ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice by inducing CD4+ T cell apoptosis

Arsenic trioxide ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice by inducing CD4+ T cell apoptosis

Abstract Background Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system characterized by severe white matter demyelination. Because of its complex pathogenesis, there is no definite cure for MS. Experimental autoimmune encephalomyelitis (EAE) is an ideal animal model...

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Bibliographic Details
Main Authors: Ke An, Meng-Jiao Xue, Jia-Ying Zhong, Sheng-Nan Yu, Tian-Shu Lan, Zhong-Quan Qi, Jun-Jie Xia
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Neuroinflammation
Subjects:
Experimental autoimmune encephalomyelitis
Arsenic trioxide
CD4+ T cells
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12974-020-01829-x

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http://link.springer.com/article/10.1186/s12974-020-01829-x

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