Alternative lengthening of telomeres (ALT) influences survival in soft tissue sarcomas: a systematic review with meta-analysis

Alternative lengthening of telomeres (ALT) influences survival in soft tissue sarcomas: a systematic review with meta-analysis

Abstract Background Alternative lengthening of telomeres (ALT) is a telomerase-independent mechanism used by a broad range of neoplasms to maintain telomere length, permitting uncontrolled replication during their progression. ALT has been described in different types of sarcoma, but a comprehensive...

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Bibliographic Details
Main Authors: Rita T. Lawlor, Nicola Veronese, Antonio Pea, Alessia Nottegar, Lee Smith, Camilla Pilati, Jacopo Demurtas, Matteo Fassan, Liang Cheng, Claudio Luchini
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Cancer
Subjects:
ALT
Sarcoma
Mesenchymal
Prognosis
Survival
ATR
Online Access:http://link.springer.com/article/10.1186/s12885-019-5424-8

Internet

http://link.springer.com/article/10.1186/s12885-019-5424-8

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