GSK-3β phosphorylation of functionally distinct tau isoforms has differential, but mild effects

<p>Abstract</p> <p>Background</p> <p>Tau protein exists as six different isoforms that differ by the inclusion or exclusion of exons 2, 3 and 10. Exon 10 encodes a microtubule binding repeat, thereby resulting in three isoforms with three microtubule binding repeats (3R...

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Bibliographic Details
Main Authors: Gamblin T Chris, Voss Kellen
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/4/1/18