A meta-analysis of caspase 9 polymorphisms in promoter and exon sequence on cancer susceptibility.

BACKGROUND: Caspases are important regulators and executioners in apoptosis pathway and have been defined as either tumor suppressors or oncogenes. Polymorphisms in promoter and exon of caspase 9 were shown to confer genetic susceptibility to multiple cancers, but the results were inconsistent. To a...

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Bibliographic Details
Main Authors: Wei Xu, Shengqiang Jiang, Yuanyuan Xu, Bo Chen, Yan Li, Feng Zong, Weihong Zhao, Jianqing Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3355128?pdf=render