Protective effect of bone marrow mesenchymal stem cell-derived exosomes against the reproductive toxicity of cyclophosphamide is associated with the p38MAPK/ERK and AKT signaling pathways

Protective effect of bone marrow mesenchymal stem cell-derived exosomes against the reproductive toxicity of cyclophosphamide is associated with the p38MAPK/ERK and AKT signaling pathways

Spermatogenic dysfunction caused by cyclophosphamide (CP) chemotherapy has seriously influenced the life quality of patients. Unfortunately, treatments for CP-induced testicular spermatogenic dysfunction are limited, and the molecular mechanisms are not fully understood. For the first time, here, we...

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Bibliographic Details
Main Authors: Xiao-Bin Guo, Jia-Wen Zhai, Hui Xia, Jian-Kun Yang, Jun-Hao Zhou, Wen-Bin Guo, Cheng Yang, Ming Xia, Kang-Yi Xue, Cun-Dong Liu, Qi-Zhao Zhou
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Asian Journal of Andrology
Subjects:
bone marrow mesenchymal stem cells; cyclophosphamide; exosomes; reproductive toxicity
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2021;volume=23;issue=4;spage=386;epage=391;aulast=Guo

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2021;volume=23;issue=4;spage=386;epage=391;aulast=Guo

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