Improving pairwise comparison of protein sequences with domain co-occurrence.

Comparing and aligning protein sequences is an essential task in bioinformatics. More specifically, local alignment tools like BLAST are widely used for identifying conserved protein sub-sequences, which likely correspond to protein domains or functional motifs. However, to limit the number of false...

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Bibliographic Details
Main Authors: Christophe Menichelli, Olivier Gascuel, Laurent Bréhélin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5766236?pdf=render