Shaping nanoparticle diffusion through biological barriers to drug delivery

Nanoparticle drug delivery systems encounter many biological barriers, such as the extracellular matrix and mucus gels, that they must bypass to gain access to target cells. A design parameter that has recently gained attention is nanoparticle shape, as it has been shown elongated rod–shaped nanopar...

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Bibliographic Details
Main Authors: Benjamin J. Lee, Yahya Cheema, Shahed Bader, Gregg A. Duncan
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:JCIS Open
Online Access:http://www.sciencedirect.com/science/article/pii/S2666934X21000246