Drug-specific Treg cells are induced during desensitization procedure for rituximab and tocilizumab in patients with anaphylaxis

Drug-specific Treg cells are induced during desensitization procedure for rituximab and tocilizumab in patients with anaphylaxis

Abstract Biologic agents (BA) are able to induce an adaptive immune response in a proportion of exposed patients with the onset of anti-drug antibodies (ADA), which are usually responsible for hypersensitivity reactions (HR). Drug desensitization (DD) for BA allows transient clinical tolerance to th...

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Bibliographic Details
Main Authors: Alessandra Vultaggio, Francesca Nencini, Susanna Bormioli, Elena Silvestri, Laura Dies, Emanuele Vivarelli, Enrico Maggi, Andrea Matucci
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91851-7

Internet

https://doi.org/10.1038/s41598-021-91851-7

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