Escape from X inactivation varies in mouse tissues.
X chromosome inactivation (XCI) silences most genes on one X chromosome in female mammals, but some genes escape XCI. To identify escape genes in vivo and to explore molecular mechanisms that regulate this process we analyzed the allele-specific expression and chromatin structure of X-linked genes i...
Main Authors: | Joel B Berletch, Wenxiu Ma, Fan Yang, Jay Shendure, William S Noble, Christine M Disteche, Xinxian Deng |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-03-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4364777?pdf=render |
Similar Items
-
Identification of genes escaping X inactivation by allelic expression analysis in a novel hybrid mouse model
by: Joel B. Berletch, et al.
Published: (2015-12-01) -
X Inactivation and Escape: Epigenetic and Structural Features
by: He Fang, et al.
Published: (2019-10-01) -
Female bias in Rhox6 and 9 regulation by the histone demethylase KDM6A.
by: Joel B Berletch, et al.
Published: (2013-05-01) -
Genomic responses to abnormal gene dosage: the X chromosome improved on a common strategy.
by: Xinxian Deng, et al.
Published: (2010-02-01) -
Single-cell landscape of nuclear configuration and gene expression during stem cell differentiation and X inactivation
by: Giancarlo Bonora, et al.
Published: (2021-09-01)