Escape from X inactivation varies in mouse tissues.

X chromosome inactivation (XCI) silences most genes on one X chromosome in female mammals, but some genes escape XCI. To identify escape genes in vivo and to explore molecular mechanisms that regulate this process we analyzed the allele-specific expression and chromatin structure of X-linked genes i...

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Bibliographic Details
Main Authors: Joel B Berletch, Wenxiu Ma, Fan Yang, Jay Shendure, William S Noble, Christine M Disteche, Xinxian Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4364777?pdf=render