Overexpression of EGFR in head and neck squamous cell carcinoma is associated with inactivation of SH3GL2 and CDC25A genes.

The aim of this study is to understand the mechanism of EGFR overexpression in head and neck squamous cell carcinoma (HNSCC). For this reason, expression/mutation of EGFR were analyzed in 30 dysplastic head and neck lesions and 148 HNSCC samples of Indian patients along with 3 HNSCC cell lines. In a...

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Main Authors: Guru Prasad Maiti, Pinaki Mondal, Nupur Mukherjee, Amlan Ghosh, Susmita Ghosh, Sanjib Dey, Jayanta Chakrabarty, Anup Roy, Jaydip Biswas, Susanta Roychoudhury, Chinmay Kumar Panda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3651136?pdf=render