Ascorbic acid pre-treated quartz stimulates TNF-α release in RAW 264.7 murine macrophages through ROS production and membrane lipid peroxidation

Ascorbic acid pre-treated quartz stimulates TNF-α release in RAW 264.7 murine macrophages through ROS production and membrane lipid peroxidation

<p>Abstract</p> <p>Background</p> <p>Inhalation of crystalline silica induces a pulmonary fibrotic degeneration called silicosis caused by the inability of alveolar macrophages to dissolve the crystalline structure of phagocytosed quartz particles. Ascorbic acid is capa...

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Bibliographic Details
Main Authors: Benvenuto Federica, Ferraris Chiara, Pozzolini Marina, Magnone Mirko, Scarfì Sonia, Benatti Umberto, Giovine Marco
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/10/1/25

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http://respiratory-research.com/content/10/1/25

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