Comparative functional genomic screens of three yeast deletion collections reveal unexpected effects of genotype in response to diverse stress
The Yeast Knockout (YKO) collection has provided a wealth of functional annotations from genome-wide screens. An unintended consequence is that 76% of gene annotations derive from one genotype. The nutritional auxotrophies in the YKO, in particular, have phenotypic consequences. To address this issu...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2017-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160330 |