Mucoadhesive microemulsion of ibuprofen: design and evaluation for brain targeting efficiency through intranasal route

This study aimed at designing mucoadhesive microemulsion gel to enhance the brain uptake of Ibuprofen through intranasal route. Ibuprofen loaded mucoadhesive microemulsion (MMEI) was developed by incorporating polycarbophil as mucoadhesive polymer into Capmul MCM based optimal microemulsion (MEI) an...

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Bibliographic Details
Main Authors: Surjyanarayan Mandal, Snigdha Das Mandal, Krishna Chuttani, Bharat Bhushan Subudhi
Format: Article
Language:English
Published: Universidade de São Paulo 2015-09-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300721&lng=en&tlng=en