Malarone treatment failure not associated with previously described mutations in the cytochrome b gene

<p>Abstract</p> <p>Malarone<sup>® </sup>(atovaquone-proguanil) is an effective drug for the treatment and prophylaxis of multidrug-resistant falciparum malaria. However, first cases of resistance have been reported, which are associated with mutations at codon 268 of th...

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Bibliographic Details
Main Authors: Mockenhaupt Frank P, Gruss Holger, Muehlen Marion, Wichmann Ole, Suttorp Norbert, Jelinek Tomas
Format: Article
Language:English
Published: BMC 2004-06-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/3/1/14