Pharmacokinetics-Based Chronoefficacy of Semen Strychni and Tripterygium Glycoside Tablet Against Rheumatoid Arthritis

Pharmacokinetics-Based Chronoefficacy of Semen Strychni and Tripterygium Glycoside Tablet Against Rheumatoid Arthritis

Rheumatoid arthritis is a systemic autoimmune disease characterized by synovial inflammation and bone destruction. Identifying drugs with time-varying efficacy and toxicity, and elucidating the mechanisms would help to improve treatment efficacy and reduce adverse effects. Here, we aimed to determin...

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Bibliographic Details
Main Authors: Jingpan Lin, Lu Gao, Yanke Lin, Shuai Wang, Zemin Yang, Shujing Ren, Min Chen, Baojian Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
semen strychni
tripterygium glycoside tablet
chronoefficacy
dosing time
pharmacokinetics
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.673263/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.673263/full

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