Cellular Immunotherapy: Using Alloreactivity to Induce Anti-Leukemic Responses without Prolonged Persistence of Donor Cells

A goal of cancer immunologists is to harness cellular immune responses to achieve anti-cancer responses. One of the strongest activating stimuli for the immune system is the encounter with cells expressing allogeneic HLA molecules. While alloreactive responses can negatively impact of the outcome of...

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Bibliographic Details
Main Authors: Loren D. Fast, John Reagan, Peter Quesenberry
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Medical Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3271/1/1/37