Transcriptome investigation of anti‐inflammation and immuno‐regulation mechanism of taurochenodeoxycholic acid

Transcriptome investigation of anti‐inflammation and immuno‐regulation mechanism of taurochenodeoxycholic acid

Abstract Background Taurochenodeoxycholic acid (TCDCA) is one of the major active components in bile acid. It was proven to have inhibitory activities on inflammation and also participate in host immuno-regulation. TCDCA exerts anti-inflammatory and immuno-regulatory effects through the glucocortico...

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Bibliographic Details
Main Authors: Lige Bao, Dacheng Hao, Xu Wang, Xiuling He, Wei Mao, Peifeng Li
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Pharmacology and Toxicology
Subjects:
Taurochenodeoxycholic acid
RNA sequencing
Fibroblast‐like synoviocytes
Glucocorticoid receptor
Serine/arginine-rich splicing factor-9
Online Access:https://doi.org/10.1186/s40360-021-00491-0

Internet

https://doi.org/10.1186/s40360-021-00491-0

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