Evolution of a higher intracellular oxidizing environment in Caenorhabditis elegans under relaxed selection.

We explored the relationship between relaxed selection, oxidative stress, and spontaneous mutation in a set of mutation-accumulation (MA) lines of the nematode Caenorhabditis elegans and in their common ancestor. We measured steady-state levels of free radicals and oxidatively damaged guanosine nucl...

Full description

Bibliographic Details
Main Authors: Joanna Joyner-Matos, Kiley A Hicks, Dustin Cousins, Michelle Keller, Dee R Denver, Charles F Baer, Suzanne Estes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3679170?pdf=render