Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation.

Cellular electrophysiology experiments, important for understanding cardiac arrhythmia mechanisms, are usually performed with channels expressed in non myocytes, or with non-human myocytes. Differences between cell types and species affect results. Thus, an accurate model for the undiseased human ve...

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Bibliographic Details
Main Authors: Thomas O'Hara, László Virág, András Varró, Yoram Rudy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3102752?pdf=render