Standardized <i>Bacopa monnieri</i> Extract Ameliorates Learning and Memory Impairments through Synaptic Protein, Neurogranin, Pro-and Mature BDNF Signaling, and HPA Axis in Prenatally Stressed Rat Offspring

Standardized <i>Bacopa monnieri</i> Extract Ameliorates Learning and Memory Impairments through Synaptic Protein, Neurogranin, Pro-and Mature BDNF Signaling, and HPA Axis in Prenatally Stressed Rat Offspring

Prenatal stress (PNS) influences offspring neurodevelopment, inducing anxiety-like behavior and memory deficits. We investigated whether pretreatment of <i>Bacopa monnieri</i> extract (CDRI-08/BME) ameliorates PNS-induced changes in signaling molecules, and changes in the behavior of Wis...

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Bibliographic Details
Main Authors: Karunanithi Sivasangari, Koilmani Emmanuvel Rajan
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
prenatal stress
<i>Bacopa monnieri</i>
caspase-3
synaptophysin
<i>N</i>-methyl-D-aspartate receptor (NMDAR)
brain-derived neurotropic factor (BDNF)
Online Access:https://www.mdpi.com/2076-3921/9/12/1229

Internet

https://www.mdpi.com/2076-3921/9/12/1229

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