TGF-β1-induced epithelial-mesenchymal transition promotes monocyte/macrophage properties in breast cancer cells

Breast cancer progression towards metastatic disease is linked to re-activation of epithelial-mesenchymal transition (EMT), a latent developmental process. Breast cancer cells undergoing EMT lose epithelial characteristics and gain the capacity to invade the surrounding tissue and migrate away from...

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Bibliographic Details
Main Authors: Joel eJohansson, Vedrana eTabor, Anna eWikell, Sirpa eJalkanen, Jonas eFuxe
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Oncology
Subjects:
EMT
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00003/full