Ortho‐Quinone Methide Driven Synthesis of New O,N‐ or N,N‐Heterocycles

Ortho‐Quinone Methide Driven Synthesis of New O,N‐ or N,N‐Heterocycles

Abstract To synthesize functionalized Mannich bases that can serve two different types of ortho‐quinone methide (o‐QM) intermediates, 2‐naphthol and 6‐hydroxyquinoline were reacted with salicylic aldehyde in the presence of morpholine. The Mannich bases that can form o‐QM and aza‐o‐QM were also synt...

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Bibliographic Details
Main Authors: Dr. István Szatmári, Khadija Belasri, Dr. Matthias Heydenreich, Dr. Andreas Koch, Prof. Dr. Erich Kleinpeter, Prof. Dr. Ferenc Fülöp
Format: Article
Language:English
Published: Wiley-VCH 2019-07-01
Series:ChemistryOpen
Subjects:
ortho-quinone methide (o-QMs)
modified Mannich reaction
cycloaddition
NMR spectroscopy
conformational analysis
DFT calculations
Online Access:https://doi.org/10.1002/open.201900150

Internet

https://doi.org/10.1002/open.201900150

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